For
atherosclerosis, diabetes is considered as important risk factor. In diabetes
mellitus patients, atherosclerotic vascular disease is most important cause of
morbidity and mortality. In the pathogenesis of Cardiovascular Diseases (CVD)and stroke inflammation plays a key role. Serum concentration of CRP can
increase more than 1000 times upon inflammation and with half-life of 19 h; CRP
is stable marker of the inflammatory process. In the process of initiation and
progression of atherothrombotic, inflammation is the central role in the
triggering of CVD events. The interaction of innate immune system with
atherosclerosis is established in vascular biology.
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